NFL Week 4: Best Picks Against the Spread and Totals

Author: Henri Ojala | Fact checker: Tommi Valtonen · Updated: · Ad Disclosure
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Best NFL Week 4 Picks Against the Spread

In one of the last full slate of games before the first bye of the season, we’ve gathered the best NFL picks against the spread for Week 4. Underdogs have been spoiling things thus far. Will this be the week that the market corrects itself?

NFL Week 4 Game Best Picks
Minnesota Vikings (3-0) at Green Bay Packers (2-1) Vikings +2.5
Pittsburgh Steelers (3-0) at Indianapolis Colts (1-2) Steelers -1.5, Under 39.5
Denver Broncos (1-2) at New York Jets (2-1) Jets -7.5
Cincinnati Bengals (0-3) at Carolina Panthers (1-2) Bengals -4
Houston Texans (2-1) at Jacksonville Jaguars (0-3) Texans -4
Buffalo Bills (3-0) at Baltimore Ravens (1-2) Bills +2.5

Minnesota Vikings (3-0) at Green Bay Packers (2-1)

Point Spread: GB -2.5
Total: 43.5 o/u
Pick: MIN +2.5
Green Bay head coach Matt LaFleur has a successful 19-11 ATS record versus NFC North opponents. However, the undefeated Vikings are a perfect 3-0 ATS. Quarterback Sam Darnold leads the NFL with eight touchdowns, and the Vikings’ defense ranks second in scoring, allowing only 10.0 ppg. Expect the Vikings to cover.

Pittsburgh Steelers (3-0) at Indianapolis Colts (1-2)

Point Spread: PIT -1.5
Total: 39.5 o/u
Pick: PIT -1.5, Under 39.5
The Steelers boast the NFL’s best scoring defense, allowing just 8.7 ppg. Despite the Colts’ struggles on offense, RB Jonathan Taylor is back in form. The game is expected to be a low-scoring, defensive battle, making the Steelers and the under attractive picks.

Denver Broncos (1-2) at New York Jets (2-1)

Point Spread: NYJ -7.5
Total: 39.5 o/u
Pick: NYJ -7.5
After an ugly season opener, the Jets have won two straight and are coming off extended rest. Aaron Rodgers thrives with rest and excels against rookie QBs. The Broncos’ struggles continue, and the Jets are poised to cover.

Cincinnati Bengals (0-3) at Carolina Panthers (1-2)

Point Spread: CIN -4
Total: 47 o/u
Pick: CIN -4
The Bengals, despite their record, have lost three close games. “Bounce Back Joey” Burrow aims to lead them to their first win. Meanwhile, the Panthers’ offense has seen a spark with veteran QB Andy Dalton. The Bengals are hungry for their first win and should cover.

Houston Texans (2-1) at Jacksonville Jaguars (0-3)

Point Spread: HOU -4
Total: 45.5 o/u
Pick: HOU -4
The Texans, led by rookie QB CJ Stroud, face the winless Jaguars. Jacksonville’s offense has been struggling, averaging just 13.3 ppg, and their defense ranks poorly. Houston is expected to take advantage of the Jaguars’ woes.

Buffalo Bills (3-0) at Baltimore Ravens (1-2)

Point Spread: BAL -2.5
Total: 46.5 o/u
Pick: BUF +2.5
Sunday Night Football features a potential playoff matchup between the Bills and Ravens. Despite trends favoring the Ravens on SNF, the Bills’ hot start makes them a strong underdog pick to cover the +2.5.

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Internationally renowned author Henri Ojala has spent more than a decade mastering the ins and outs of the gambling industry, focusing on online poker, sports betting, and casino games. With over 10 years of experience in the gambling industry, Henri shares his extensive knowledge of strategies, odds, and risk management, earning him recognition as an authority in the online casino field.